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When used sublingually, buprenorphine/naloxone and buprenorphine have similar clinical effects and are interchangeable; however, before switching between buprenorphine/naloxone and buprenorphine, the prescriber and patient should agree to the change, and the patient should be monitored in case a need to readjust the dose occurs.

Suboxone, Reckitt Benckiser as the manufacturer, its primary use is to treat opioid addiction (in higher doses) and to control moderate chronic pain (in smaller doses).  Also, Suboxone contains buprenorphine as well as the opioid antagonist naloxone, which deters intravenous injection.  The estimated ratio of buprenorphine to naloxone in Suboxone is 4:1. Subutex, however, contains only buprenorphine unlike its counterpart Suboxone.

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Some medicines can interact with buprenorphine and naloxone and cause a serious condition to call serotonin syndrome.

Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting.

Ask your doctor before making any changes in how or when you take your medications.

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Suboxone is a medication used to treat opioid addiction. Opioids are medicines that are used to treat moderate to severe pain. Thus they can easily cause physical dependence and addiction.

This drug is a combination of buprenorphine and naloxone. Buprenorphine belongs to a class of drugs called opioid partial agonists, which help relieve symptoms of opiate withdrawal. While naloxone is in a class of drugs called opioid antagonists, which reverse the effects of narcotics.